University of Bristol and Severn Foundation School 

 

We offer a wide range of project areas within the domains outlined below.  Each programme has an identified lead senor academic clinician and multiple potential academic project supervisors.  Within this framework we are able to flexibly develop project ideas with trainees to design achievable, productive studies to make the most of the research block.

For any general Academic Programme queries please contact:
Professor Tony Pickering AFP Director.

 

  

 

Anaesthetics, Pain and Critical Care Sciences

Our research covers a broad spectrum from basic science investigations on pain and analgesia, cardiovascular and respiratory control, and mechanisms of anaesthesia to clinical studies in patient populations.  We have a growing cohort of trainee academics whose research is conducted within the Bristol Neuroscience and Cardiovascular themes at the University of Bristol.  From a core within the School of Physiology, Pharmacology and Neuroscience, we collaborate with internationally recognised research groups on topics ranging from cell signalling and neuropharmacology to cardiovascular/respiratory function and the study of sensory and motor systems in the intact brain. The successful applicants will be offered a broad choice of research projects and supervisors (examples of recent project areas include pain control, regulation of cerebral circulation, mechanisms of hypertension, respiratory and sympathetic control and wound healing). These projects are selected to provide experience of the use of cutting edge bioscience to address current clinical problems.

Posts: 2 per year maximum

Contact: Dr Tony Pickering 
Tel: (0117) 331 2311 - University of Bristol - Physiology and Pharmacology

 

Clinical Epidemiology / Public Health

Clinical epidemiology is the discipline that determines causes of disease in populations and combined with health services research evaluates diagnostic, prognostic and clinical interventions. The Department of Population Health Science is a leading centre for life course and genetic epidemiology, health services research and public health in the UK. The attachment will enable the trainee to learn about specific epidemiological and statistical methods through the hands-on analysis of data that has already been collected, leading to a peer-reviewed publication. There may also be opportunities to observe or help with data collection. Current areas of interest include cardiometabolic disease, prostate and other cancers, early life origins of chronic diseases, Mendelian Randomisation, mental health and neurodegenerative disorders.

Posts: 2 per year maximum

Contact: Professor David Gunnell

 

Neurology

We focus on research into Dementia, Movement disorders, Neonatal brain injury, Multiple Sclerosis and stem cell therapies – collectively forming the Institute of Clinical Neurosciences. This is now housed predominantly in new purpose built clinical and laboratory research centres in Southmead Hospital. We take a multidisciplinary approach ranging from basic neurobiological investigations, through experimental medicine and clinical trials, MRI imaging and human brain bank studies. Our overriding aim is to address some of the key therapeutic challenges facing our population.

Posts 2 per year maximum

Contact: Dr Elizabeth Coulthard

 

Nutrition

We aim to translate knowledge developed from our work on causal associations, drawn from population and clinical studies, to develop interventions that improve the health of people with conditions related to poor nutrition. We provide the necessary resources to run a programme of world-leading clinical nutrition research. Research areas include nutrition in people with prostate cancer, optimising nutrition in children with chronic disease, pre and post-surgical feeding and sedentary behaviour in people with diabetes. These areas are supported by a methodological core team to transfer ideas, translate into preliminary feasibility trials and provide research evidence.

Posts 2 per year maximum

Contact: Professor Andy Ness Biomedical Research Unit (BRU) in Nutrition

 

Paediatrics

These posts will be attached to the clinical and research teams based around the purpose built Bristol Royal Hospital for Children, a tertiary referral centre for the South West. Paediatric research is a particular strength in Bristol and we are able to offer excellent opportunities in a range of areas including:

 Infectious diseases (joint with microbiology) focuses on the diagnosis, pathogenesis and immune responses to respiratory bacteria and viruses. The group has a particular interest in inter-species interactions and human mucosal immune responses. 

Endocrine/Metabolic offers lab-based research using primary cell culture of muscle and fat studying insulin resistance and nutrition. 

The Centre for Child and Adolescent Health with research in:  Nutrition in early childhood, Child development and disability, Children’s palliative care and complex health needs, and Childhood injury. We also have a strong interest in international child health and have collaborations with overseas partners. 

Renal Laboratory Research - Glomerular and Renal Cell Biology (Moin Saleem, Professor of Paediatric Renal Medicine; Richard Coward, Professor of Renal Medicine and MRC Senior Clinical Fellow in Paediatric Nephrology):  We have an active and vibrant research group examining renal biology. Bristol Renal consists of more than 30 members of both clinical and non-clinical backgrounds from both paediatric and adult backgrounds. We have a mix of laboratory technicians, clinical and non-clinical PhD students, MD students post-doctoral researchers and a senior non-clinical Lecturer, Dr Gavin Welsh.  We are located in fully equipped laboratories in the Dorothy Hodgkin building which is less than 3 minutes from the Children’s hospital. We have weekly lab meeting here to which other clinicians are invited.  We perform world-class basic science research into the molecular mechanisms that cause kidney disease in our patients. 

Cardiology with particular interest in pulmonary hypertension aligned to the BRU in the Bristol Heart Institute.

Posts: 4 per year maximum

Contacts:

Programme Lead: Professor Richard Coward
programme Lead: Professor Esther Crawley

Endocrinology: Professor Julian Hamilton Shield

Renal: Professor Moin Saleem

 

 

Primary Health Care

Academic primary care is situated in the Department of Population Health Science. In the 2008 RAE, 70% of our research was rated either 4* or 3* (of international standing). We have a long and strong track record of supporting medical students on SSCs and electives, and training academic GPs with particular success in supporting would be academic GPs as AF2s, academic GP registrars and training fellows. Our current areas of interest include primary care mental health including domestic violence, service delivery, infectious diseases in children, childhood obesity and cardio-vascular medicine. We use a wide range of research methodologies.

Posts: 2 per year maximum

Contact: Professor Debbie Sharp
Tel: (0117) 3314543 - University of Bristol - Centre for Academic Primary Care

 

Psychiatry

Psychiatric research is now benefiting from the substantial growth in neuroscience over the past 10-15 years and this will have increasing influence over new treatments and understanding of mechanisms: biological, psychological and social. We run a wide range of research projects in the Centre of Academic Mental Health Research, including studies involving experimental psychology designs, randomised controlled trials and large population based longitudinal studies such as ALSPAC.

Posts: 2 per year maximum

Contact: Dr Jonathan Evans Consultant Senior Lecturer in Psychiatry
Tel: (0117) 331 4027

 

Renal

The Academic Renal Unit has an international reputation for the study of glomerular diseases, such as diabetic nephropathy, and for work in vascular biology linking renal and cardiovascular disease. The ARU comprises forty researchers providing a supportive, friendly and stimulating environment for a range of laboratory-based projects encompassing cell and molecular biology, in vivo models and genetics. 

Work in renal epidemiology and health services research, centred in the UK Renal Registry in collaboration with the Department of Population Health Science, includes chronic kidney disease, acute kidney injury, quality of life and pragmatic evaluation of quality improvement initiatives.

Posts: 2 per year maximum

Contact: Dr Simon Satchell Reader in Renal Medicine
Tel: (0117) 331 3081

 

Respiratory

Respiratory disease places a large burden on society in terms of disability and premature mortality, costing the NHS £6.6 billion per year. The Academic Respiratory Unit is a multi-disciplinary team and our aim is to improve the diagnosis, management and treatment of lung disease by a translational research strategy including: Cell Biology - focused on lung injury and repair; Respiratory Neuroscience - functional MR-imaging in lung disease; Pleural Clinical Trials – supporting NIHR Portfolio & commercial studies.

Posts 2 per year maximum

Contact: Professor Nick Maskell

 

Surgery

The trainee will join the thriving Surgical Trials Centre led by Jane Blazeby, Professor of Surgery, based at the Department of Population health Science. This includes 3 academic clinical lecturers, an academic clinical fellow and 5 surgical PhD students. The surgical trials centre works closely with the MRC ConDuCT Methodology Hub which is a multi-disciplinary team of methodologists including statisticians, social scientists, health economists and clinicians. Within the trials centres are several on going randomised controlled trials in surgery of all specialities. Trainees will be offered a choice of health services research projects aimed to provide experience of designing and conducting randomised trials in surgery or understanding methodology relevant to surgical trials.

Posts: 2 per year maximum

Contact: Professor Robert Hinchliffe